Erythromycin oxime is a white crystalline powder, often used as a raw material intermediate, and is easily soluble in organic solvents such as methanol and dichloromethane. The synthesis of erythromycin oxime under acidic conditions is accompanied by the acid hydrolysis reaction of erythromycin. Washing operation is required during the production process, which is carried out using the centrifugal extractor.
Erythromycin Oxime Washing Process
Washing of erythromycin oxime requires mixing, separation, water washing, and stripping.
Reduction 1: mixed phase separation, aqueous phase stripping
Reduction 2: mixed phase separation, aqueous phase stripping
Phase transfer: mixed phase separation, organic phase stripping
Protection: mixed phase separation, organic phase water washing, brine washing, aqueous phase stripping
Methylation: mixed phase separation, organic phase water washing, aqueous phase stripping
Erythromycin Oxime Washing And Extraction Equipment
From the above process flow, in this process, the main parts are extraction, water washing and stripping, and the equipment used in these parts is the centrifugal extractor.
CWL-M centrifugal extractor is a new and efficient liquid-liquid mixing separation equipment produced by Zhengzhou Tiei Extraction. The equipment model needs to be selected according to the processing volume, and the number of extraction stages needs to be selected according to the liquid-feed system.
Erythromycin Oxime Washing And Extraction Equipment Configuration
Erythromycin oxime washing and extraction equipment needs to be selected from two types: experimental model and industrial model. The experimental model can choose the CWL50-M made of fluorine material, and 2-3 units can be selected for continuous extraction experiments; the industrial equipment can choose 316L material. The specific model selection depends on the size of the processing volume. Can choose CWL250-M or CWL350-M for multiple continuous extraction, stripping and washing.
The above is an introduction to the washing process and equipment for erythromycin oxime in pharmaceutical factories. For specific process flow and equipment selection, welcome contact Tiei Extraction.
Email: sales@tieiextraction.com
Whatsapp: +86 19069612820
