In the field of pharmaceutical intermediate synthesis and API purification, n-butanol, as a commonly used extraction solvent, often faces three major technical challenges in the extraction and separation process with the mother liquor water phase: low phase separation efficiency leads to solvent entrainment loss, intermittent operation limits continuous production, and high volatility solvents pose safety hazards. The launch of Zhengzhou Tiei Extraction CWL-M series centrifugal extractor is bringing new solutions to the fine chemical industry with revolutionary technology.
Three-stage Countercurrent Extraction Technology
CWL-M series centrifugal extractor adopts the countercurrent extraction principle, and completes the continuous countercurrent contact between the extractant and the feed liquid in a closed system under the action of high-speed centrifugal force. Actual measurement data shows that for the n-butanol extraction system of phenol pharmaceutical intermediates, a single equipment can achieve an extraction efficiency of 98%, the solvent loss is reduced by 40% compared with the traditional extraction equipment, and the recovery rate of the effective ingredient is increased to 99.5%.
A case study of a listed pharmaceutical company confirmed this: In the vitamin E acetate purification project, the CWL50-M centrifugal extractor successfully reduced the number of extraction stages from 6 in the traditional process to 3, shortened the extraction time by 70%, and increased the solvent recycling rate to 92%, greatly saving the procurement cost of n-butanol.
In view of the flammable and explosive characteristics of n-butanol, the CWL-M series centrifugal extractor is equipped with a nitrogen sealing system and an antistatic coating, and the oxygen content in the equipment body can be accurately controlled below 5%. The modular quick-disassembly structure shortens the cleaning and maintenance time by 60%, and the drum components made of special materials can withstand strong corrosive environments. Equipment that has passed ATEX explosion-proof certification has been operating stably in more than 20 API companies.
Tiei Extraction CWL-M Series Centrifugal Extractor
- Process upgrade with 50% increase in extraction efficiency
- Cost optimization with 30% reduction in solvent consumption
- Quality assurance in full compliance with GMP standards
- Full life cycle service with 24/7 response
Welcome contact us for more details
Email: sales@tieiextraction.com
Whatsapp: +86 19069612820
