Active Pharmaceutical Ingredient(API) Reaction Liquid, is an important liquid used to prepare drugs and conduct biochemical experiments. It is composed of a variety of precisely proportioned chemical substances, usually with specific acid-base properties and chemical activity, and can undergo various chemical reactions under specific experimental conditions. It is widely used in pharmaceutical research, biotechnology development, and industrial production processes.
Centrifugal extractor is well known for their efficient separation capabilities and wide range of applications. Their working principle is based on the centrifugal force to separate the components in the mixture into different layers. By adjusting the speed of the centrifuge and the magnitude of the centrifugal force, the separation effect can be precisely controlled, making it an ideal choice for processing API reaction liquid.
Before centrifugal extraction, ensure that the reaction liquid has undergone necessary preliminary treatment and sample preparation. This includes pH adjustment, solvent selection, and checking the homogeneity of the mixture to ensure the stability and suitability of the reaction liquid, laying a foundation for subsequent separation steps.
Centrifugal Extractor Operation Steps
1.Pretreatment stage: In this stage, the operator needs to prepare the sample and perform necessary pretreatment, such as removing impurities or diluting the sample, to ensure that the subsequent centrifugation can proceed smoothly.
2.Sample loading and setting parameters: Load the pretreated sample into the centrifugal extractor and set key parameters such as speed and centrifugation time according to the experimental requirements. The selection of these parameters is crucial to the separation effect and needs to be optimized according to the specific application and sample characteristics.
3.Centrifugation process: Under the action of centrifugal force, the components in the sample will form different layers in the centrifuge tube according to their density, and the target components will precipitate to the bottom of the centrifuge tube.
4.Collect the target components: After the centrifugation is completed, the layers containing the target components in the centrifuge tube are collected according to the stratification. These collected samples will serve as the basis for subsequent analysis or application.
5.Post-processing and analysis: After the target components are collected, further processing may be required, such as dissolution, concentration or purification, to obtain a high-purity API reaction liquid. Quality control and analysis are then performed to ensure that the extracted target components meet the expected quality standards.
Tiei Extraction CWL-M Centrifugal Extractor
Centrifugal extractor is a new, fast, high-speed liquid-liquid extraction and separation equipment, which is fundamentally different from traditional extraction equipment such as mixer settler and extraction column in terms of working principle. Centrifugal extractor uses a motor to drive the drum to rotate at high speed. Two liquids with different densities and immiscible with each other complete mixing and mass transfer under the shear force generated by the rotation of the drum or blades, and are quickly separated under the centrifugal force generated by the high-speed rotation of the drum.
- The extraction efficiency is extremely high, reaching more than 90%.
- The energy-saving effect is obvious. Under the same processing capacity, the power consumption is only 1/3-1/10 of that of traditional equipment.
- The two phases are separated quickly, and the separation effect is very good.
- The processing capacity is large and can meet various processing capacity requirements.
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